In addition to specializing in patient care, faculty in the UF Department of Dermatology are actively engaged in on-going research programs. Our research in the treatment of the skin is propelling the department into the forefront of the dermatology research across the nation.
Clinical Trials Unit
Our goal is to enhance patient care by promoting understanding of skin diseases and supporting the development of ground breaking novel treatments.
Here you will find information about studies being conducted that require patient assistance. If you are interested in participating please use the contact information provided on the flyer provided,
Basic Science Research
Atopic dermatitis is characterized by skin barrier disruption, an aberrant adaptive immune response to environmental allergens (or antigen), susceptibility to cutaneous bacterial infections and intractable itch. Atopic dermatitis in dogs has striking similarities with the human counterpart both clinically and immunologically. As atopic dermatitis is a prevalent, chronic disease affecting 10-15% of children and up to 6% of adults in Westernized countries, studies to better understand the pathogenesis and identify new treatments have been in great demand.
This research focuses on the establishment and evolution of the infantile cutaneous microbiome and how it relates to the development of pediatric skin disease. It is likely that early priming of the cutaneous immune system is necessary to “teach” the immune system to tolerate commensal organisms. As we understand more about what organisms are present early in infancy, and how these organisms prime the immune system, we will understand more about how to prevent or treat common pediatric skin diseases. Imagine a world where we are able to apply something to the skin in infancy to prevent the development of eczema!